Tumor-Induced STAT3 Signaling in Myeloid Cells Impairs Dendritic Cell Generation by Decreasing PKCβII Abundance-Reference-Cited by-同舟云学术

Tumor-Induced STAT3 Signaling in Myeloid Cells Impairs Dendritic Cell Generation by Decreasing PKCβII Abundance

Author:

Farren Matthew R.¹,Carlson Louise M.¹,Netherby Colleen S.¹,Lindner Inna²,Li Pui-Kai³,Gabrilovich Dmitry I.⁴,Abrams Scott I.¹,Lee Kelvin P.¹⁵⁶

Affiliation:

1. Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

2. Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, FL 33136, USA.

3. College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.

4. Translational Tumor Immunology Program, The Wistar Institute, Philadelphia, PA 19104, USA.

5. Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

6. The Jacobs Family Chair of Immunology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

Abstract

Tumor-derived factors repress immune responses by reducing protein kinase C signaling in dendritic cell progenitors.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference57 articles.

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