Interferon-γ Resets Muscle Cell Fate by Stimulating the Sequential Recruitment of JARID2 and PRC2 to Promoters to Repress Myogenesis-Reference-Cited by-同舟云学术

Interferon-γ Resets Muscle Cell Fate by Stimulating the Sequential Recruitment of JARID2 and PRC2 to Promoters to Repress Myogenesis

Published:2013-12-10 Issue:305 Volume:6 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Londhe Priya¹,Davie Judith K.¹

Affiliation:

1. Department of Biochemistry and Molecular Biology and Simmons Cancer Institute, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.

Abstract

Too much interferon-γ, produced in response to inflammation, represses genes needed for muscle repair.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference62 articles.

1. Looking back to the embryo: defining transcriptional networks in adult myogenesis

2. Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

3. Myogenin gene disruption results in perinatal lethality because of severe muscle defect

4. Cellular and Molecular Regulation of Muscle Regeneration

5. Endogenous interferon-γ is required for efficient skeletal muscle regeneration

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