Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties-Reference-Cited by-同舟云学术

Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties

Published:2017-02-21 Issue:467 Volume:10 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Brust Tarsis F.¹^ORCID,Alongkronrusmee Doungkamol¹^ORCID,Soto-Velasquez Monica¹^ORCID,Baldwin Tanya A.²^ORCID,Ye Zhishi³^ORCID,Dai Mingji³,Dessauer Carmen W.²^ORCID,van Rijn Richard M.¹^ORCID,Watts Val J.¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology and Center for Drug Discovery, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907, USA.

2. Department of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

3. Department of Chemistry and Centers for Cancer Research and Drug Discovery, College of Science, Purdue University, 720 Clinic Drive, West Lafayette, IN 47907, USA.

Abstract

ST034307 is a selective AC1 inhibitor with analgesic activity.

Funder

National Institute of Mental Health

Purdue Research Foundation

Purdue Showalter Trust Award

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference55 articles.

1. Higher-order organization and regulation of adenylyl cyclases