Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S-Reference-Cited by-同舟云学术

Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S

Published:2020-10-20 Issue:654 Volume:13 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Liess Anna K. L.¹^ORCID,Kucerova Alena²^ORCID,Schweimer Kristian³^ORCID,Schlesinger Dörte²^ORCID,Dybkov Olexandr⁴^ORCID,Urlaub Henning⁵⁶,Mansfeld Jörg²⁷^ORCID,Lorenz Sonja¹^ORCID

Affiliation:

1. Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, 97080 Würzburg, Germany.

2. Cell Cycle, Biotechnology Center, Technische Universität Dresden, 01307 Dresden, Germany.

3. Biopolymers, University of Bayreuth, 95447 Bayreuth, Germany.

4. Department for Cellular Biochemistry, Max Planck Institute for Biophysical Chemistry, Göttingen, 37077 Göttingen, Germany.

5. Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, 37077 Göttingen, Germany.

6. Bioanalytics Institute for Clinical Chemistry, University Medical Center Göttingen, 37075 Göttingen, Germany.

7. Institute of Cancer Research, London SW7 3RP, UK.

Abstract

The E2 enzyme UBE2S may be stored as a dimer to prevent its degradation between mitotic cycles.

Funder

H2020 European Research Council

Deutsche Forschungsgemeinschaft

DIGSBB

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference73 articles.

1. Ubiquitin Ligases: Structure, Function, and Regulation

2. RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns

3. Structural mechanisms of HECT-type ubiquitin ligases

4. Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

5. Structural interconversions of the anaphase-promoting complex/cyclosome (APC/C) regulate cell cycle transitions

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