The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases-Reference-Cited by-同舟云学术

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

Published:2018-09-18 Issue:548 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Fafilek Bohumil¹²^ORCID,Balek Lukas¹^ORCID,Bosakova Michaela Kunova¹²^ORCID,Varecha Miroslav¹²^ORCID,Nita Alexandru¹,Gregor Tomas³^ORCID,Gudernova Iva¹,Krenova Jitka¹^ORCID,Ghosh Somadri⁴^ORCID,Piskacek Martin⁵,Jonatova Lucie¹^ORCID,Cernohorsky Nicole H.¹,Zieba Jennifer T.⁶,Kostas Michal⁷⁸,Haugsten Ellen Margrethe⁷⁸,Wesche Jørgen⁷⁸^ORCID,Erneux Christophe⁴^ORCID,Trantirek Lukas³,Krakow Deborah⁶⁹¹⁰^ORCID,Krejci Pavel¹²¹¹

Affiliation:

1. Department of Biology, Masaryk University, 62500 Brno, Czech Republic.

2. International Clinical Research Center, St. Anne’s University Hospital, 65691 Brno, Czech Republic.

3. Central European Institute of Technology, Masaryk University, 62500 Brno, Czech Republic.

4. Institut de Recherche Interdisciplinaire en Biologie Humaine et moléculaire, Université Libre de Bruxelles, 1070 Bruxelles, Belgium.

5. Department of Pathological Physiology, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.

6. Department of Orthopedic Surgery, University of California Los Angeles, CA 90095, USA.

7. Department of Tumor Biology, Institute for Cancer Research, Norwegian Radium Hospital, 0379 Oslo, Norway.

8. Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0379 Oslo, Norway.

9. Department of Human Genetics, University of California Los Angeles, CA 90095, USA.

10. Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA.

11. Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, 60200 Brno, Czech Republic.

Abstract

The scaffold function of the inositol phosphatase SHIP2 mediates sustained ERK signaling downstream of FGF receptors.

Funder

National Institutes of Health

Agency for Healthcare Research and Quality

Ministry of Education, Youth and Sports

Fonds De La Recherche Scientifique - FNRS

Fondation Rose et Jean Hoguet

Research Council of Norway

Norwegian Cancer Society

Fonds Lekime-Ropsy

Télévie fellowships

Université Libre de Bruxelles

National Program of Sustainability II

Czech Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference81 articles.

1. The paradox of FGFR3 signaling in skeletal dysplasia: Why chondrocytes growth arrest while other cells over proliferate

2. Fibroblast growth factor signaling in skeletal development and disease

3. Nosology and classification of genetic skeletal disorders: 2015 revision

4. Fibroblast growth factors and their receptors in cancer

5. Expression and Potential Role of Fibroblast Growth Factor 2 and Its Receptors in Human Embryonic Stem Cells

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