MEG3-4 is a miRNA decoy that regulates IL-1β abundance to initiate and then limit inflammation to prevent sepsis during lung infection-Reference-Cited by-同舟云学术

MEG3-4 is a miRNA decoy that regulates IL-1β abundance to initiate and then limit inflammation to prevent sepsis during lung infection

Published:2018-06-26 Issue:536 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Li Rongpeng¹²^ORCID,Fang Lizhu²^ORCID,Pu Qinqin²³,Bu Huimin¹,Zhu Pengcheng¹,Chen Zihan¹,Yu Min²,Li Xuefeng²,Weiland Timothy⁴,Bansal Arvind⁴,Ye Shui Qing⁵,Wei Yuquan³,Jiang Jianxin⁶^ORCID,Wu Min²³^ORCID

Affiliation:

1. Key Laboratory of Biotechnology for Medicinal Plants of Jiangsu Province and School of Life Sciences, Jiangsu Normal University, Xuzhou, Jiangsu 221116, P. R. China.

2. Department of Biomedical Sciences, University of North Dakota, Grand Forks, ND 58203–9037, USA.

3. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan 610041, P. R. China.

4. Altru Hospital, Grand Forks, ND 58203, USA.

5. Department of Pediatrics and Department of Biomedical and Health Informatics, Children’s Mercy Hospital, University of Missouri–Kansas City School of Medicine, Kansas City, MO 64108, USA.

6. State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, Sichuan 400042, P. R. China.

Abstract

Feedback inhibition of the microRNA decoy activity of lncRNA MEG3 tempers inflammation during lung infection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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