Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling-Reference-Cited by-同舟云学术

Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling

Author:

Stallaert Wayne¹²,Brüggemann Yannick¹³,Sabet Ola¹³⁴,Baak Lisa¹,Gattiglio Marina¹³,Bastiaens Philippe I. H.¹³^ORCID

Affiliation:

1. Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Str.11, 44227 Dortmund, Germany.

2. Department of Genetics, University of North Carolina, Chapel Hill, NC 27599–7264, USA.

3. Faculty of Chemistry and Chemical Biology, TU Dortmund, Otto-Hahn-Str. 6, 44227 Dortmund, Germany.

4. Department of Molecular Life Sciences, University of Zurich, Irchel Campus, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

Abstract

Ephrin signaling in densely crowded cells alters EGFR recycling to inhibit migration induced by EGF.

Funder

ERC Advanced grant

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference68 articles.

3. Spatial and temporal expression of angiogenic molecules during tumor growth and progression;Kumar R.;Oncol. Res.,1998

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