Kinase-Substrate Enrichment Analysis Provides Insights into the Heterogeneity of Signaling Pathway Activation in Leukemia Cells-Reference-Cited by-同舟云学术

Kinase-Substrate Enrichment Analysis Provides Insights into the Heterogeneity of Signaling Pathway Activation in Leukemia Cells

Author:

Casado Pedro¹,Rodriguez-Prados Juan-Carlos¹,Cosulich Sabina C.²,Guichard Sylvie²,Vanhaesebroeck Bart³,Joel Simon⁴,Cutillas Pedro R.¹

Affiliation:

1. Analytical Signalling Group, Centre for Cell Signalling, Barts Cancer Institute, Queen Mary University of London, London EC1B 6BQ, UK.

2. AstraZeneca, Macclesfield, Cheshire SK10 2NA, UK.

3. Cell Signalling Group, Centre for Cell Signalling, Barts Cancer Institute, Queen Mary University of London, London EC1B 6BQ, UK.

4. Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1B 6BQ, UK.

Abstract

Computational analysis of phosphoproteomics data predicts the sensitivity of leukemia cells to kinase inhibitors.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference60 articles.

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