A Kinetic Test Characterizes Kinase Intramolecular and Intermolecular Autophosphorylation Mechanisms-Reference-Cited by-同舟云学术

A Kinetic Test Characterizes Kinase Intramolecular and Intermolecular Autophosphorylation Mechanisms

Published:2013-07-02 Issue:282 Volume:6 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Dodson Charlotte A.¹²,Yeoh Sharon³,Haq Tamanna⁴,Bayliss Richard¹⁴

Affiliation:

1. Division of Structural Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

2. Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK.

3. Centre for Translational Therapeutics, University of Leicester, Henry Wellcome Laboratories for Structural Biology, Lancaster Road, Leicester LE1 9HN, UK.

4. Department of Biochemistry, University of Leicester, Henry Wellcome Laboratories for Structural Biology, Lancaster Road, Leicester LE1 9HN, UK.

Abstract

Mathematical analysis of enzyme kinetics reveals different modes of kinase autophosphorylation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference33 articles.

1. Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange

2. A Chaperone-Dependent GSK3β Transitional Intermediate Mediates Activation-Loop Autophosphorylation

3. Activation-Loop Autophosphorylation Is Mediated by a Novel Transitional Intermediate Form of DYRKs

4. Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

5. Structural Basis of Aurora-A Activation by TPX2 at the Mitotic Spindle

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2. The structural basis of the multi-step allosteric activation of Aurora B kinase;eLife;2023-05-25

3. PKD autoinhibition in trans regulates activation loop autophosphorylation in cis;Proceedings of the National Academy of Sciences;2023-02-06

4. The structural basis of the multi-step allosteric activation of Aurora B kinase;2022-11-24

5. PKD autoinhibition in trans regulates activation loop autophosphorylation in cis;2022-05-05