Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice-Reference-Cited by-同舟云学术

Abnormal mechanosensing and cofilin activation promote the progression of ascending aortic aneurysms in mice

Published:2015-10-20 Issue:399 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Yamashiro Yoshito¹,Papke Christina L.¹,Kim Jungsil²,Ringuette Lea-Jeanne³,Zhang Qing-Jun⁴,Liu Zhi-Ping⁴,Mirzaei Hamid⁵,Wagenseil Jessica E.²,Davis Elaine C.³,Yanagisawa Hiromi¹⁶

Affiliation:

1. Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

2. Department of Mechanical Engineering and Materials Science, Washington University, St. Louis, MO 63130, USA.

3. Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec H3A 0C7, Canada.

4. Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

5. Department of Biochemistry and Proteomics Core Unit, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

6. Life Science Center of Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577, Japan.

Abstract

Aortic aneurysms may form when smooth muscle cells cannot respond appropriately to external mechanical forces.

Funder

NIH

NIH Institutional Training in Cardiovascular Research

NIH Postdoctoral fellowship

American Heart Association

Natural Sciences and Engineering Council of Canada

The Robert A. Welch Foundation

Ministry of Education, Culture, Sports, Science and Technology of Japan

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference63 articles.

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