Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas-Reference-Cited by-同舟云学术

Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas

Published:2015-12-08 Issue:406 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Zhang Lei¹,Kundu Soumi¹,Feenstra Tjerk¹,Li Xiujuan¹,Jin Chuan¹,Laaniste Liisi¹,El Hassan Tamador Elsir Abu²,Ohlin K. Elisabet¹,Yu Di¹,Olofsson Tommie¹,Olsson Anna-Karin³,Pontén Fredrik¹,Magnusson Peetra U.¹,Nilsson Karin Forsberg¹,Essand Magnus¹,Smits Anja²,Dieterich Lothar C.¹,Dimberg Anna¹

Affiliation:

1. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, The Rudbeck Laboratory, 75185 Uppsala, Sweden.

2. Department of Neuroscience, Neurology, Uppsala University, 751 85 Uppsala, Sweden.

3. Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Biomedical Center, Box 582, SE-75123 Uppsala, Sweden.

Abstract

Secretion of pleiotrophin by aggressive gliomas triggers the formation of abnormal blood vessels by endothelial cells.

Funder

Swedish Cancer Society

Swedish Childhood Cancer Society

Swedish Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference56 articles.

1. Glioblastoma and Other Malignant Gliomas