Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple-Reference-Cited by-同舟云学术

Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple

Published:2018-02-27 Issue:519 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Aznar Nicolas¹^ORCID,Ear Jason¹^ORCID,Dunkel Ying¹,Sun Nina¹,Satterfield Kendall¹^ORCID,He Fang¹,Kalogriopoulos Nicholas A.¹,Lopez-Sanchez Inmaculada¹,Ghassemian Majid²,Sahoo Debashis³⁴,Kufareva Irina⁵^ORCID,Ghosh Pradipta¹⁶⁷^ORCID

Affiliation:

1. Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

2. Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.

3. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.

4. Department of Computer Science and Engineering, Jacobs School of Engineering, University of California, San Diego, La Jolla, CA 92093, USA.

5. Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.

6. Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

7. Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.

Abstract

The protein Daple coordinates cross-talk among growth factor receptors, Wnt, and G protein–coupled signaling pathways to facilitate tumor progression.

Funder

National Institutes of Health

National Cancer Institute

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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