Interplay Between the Oxidoreductase PDIA6 and microRNA-322 Controls the Response to Disrupted Endoplasmic Reticulum Calcium Homeostasis-Reference-Cited by-同舟云学术

Interplay Between the Oxidoreductase PDIA6 and microRNA-322 Controls the Response to Disrupted Endoplasmic Reticulum Calcium Homeostasis

Published:2014-06-10 Issue:329 Volume:7 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Groenendyk Jody¹,Peng Zhenling²,Dudek Elzbieta¹,Fan Xiao²,Mizianty Marcin J.²,Dufey Estefanie³⁴,Urra Hery³⁴,Sepulveda Denisse³⁴,Rojas-Rivera Diego³⁴,Lim Yunki⁵,Kim Do Han⁵,Baretta Kayla¹,Srikanth Sonal⁶,Gwack Yousang⁶,Ahnn Joohong⁷,Kaufman Randal J.⁸,Lee Sun-Kyung⁷,Hetz Claudio³⁴⁹,Kurgan Lukasz²,Michalak Marek¹

Affiliation:

1. Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2S7, Canada.

2. Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta T6G 2V4, Canada.

3. Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.

4. Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, University of Chile, Santiago, Chile.

5. College of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 500-712, Korea.

6. Department of Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA.

7. Department of Life Science, BK21 PLUS Life Science for BDR team, The Research Institute of Natural Sciences, Hanyang University, Seoul 133-791, Korea.

8. Degenerative Disease Research Program, Center for Neuroscience, Aging, and Stem Cell Research, Cancer Center, Sanford Burnham Medical Research Institute, La Jolla, CA 92037, USA.

9. Neurounion Biomedical Foundation, Santiago, Chile.

Abstract

Depletion of Ca 2+ in the endoplasmic reticulum favors activation of a stress response involving IRE1α.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference80 articles.

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2. The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

3. The impact of the unfolded protein response on human disease

4. Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells

5. InterfERing with endoplasmic reticulum stress

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