Host mitochondria influence gut microbiome diversity: A role for ROS-Reference-Cited by-同舟云学术

Host mitochondria influence gut microbiome diversity: A role for ROS

Published:2019-07-02 Issue:588 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Yardeni Tal¹^ORCID,Tanes Ceylan E.²,Bittinger Kyle²,Mattei Lisa M.²,Schaefer Patrick M.¹,Singh Larry N.¹^ORCID,Wu Gary D.³^ORCID,Murdock Deborah G.¹^ORCID,Wallace Douglas C.¹⁴^ORCID

Affiliation:

1. Center for Mitochondrial and Epigenomic Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA, USA.

2. Division of Gastroenterology, Hepatology, and Nutrition, Children’s Hospital of Philadelphia, Philadelphia, PA, USA.

3. Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

4. Department of Pediatrics, Division of Human Genetics and Metabolism, University of Pennsylvania, Philadelphia, PA, USA.

Abstract

Inherited genetic variations in mitochondrial function shape the gut microbiota species diversity.

Funder

NIH Office of the Director

PennCHOP Microbiome Pilot Grant

PennCHOP Microbiome Program

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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