Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α 2a -adrenergic receptors-Reference-Cited by-同舟云学术

Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α 2a -adrenergic receptors

Published:2021-12-21 Issue:714 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Yim Yun Young¹^ORCID,McDonald W. Hayes²^ORCID,Betke Katherine M.¹,Kaya Ali¹^ORCID,Hyde Karren¹,Erreger Kevin¹^ORCID,Gilsbach Ralf³⁴^ORCID,Hein Lutz⁴,Hamm Heidi E.¹^ORCID

Affiliation:

1. Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.

2. Department of Biochemistry and Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN 37232, USA.

3. Fachbereich Medizin, Institute for Cardiovascular Physiology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

4. Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.

Abstract

The Gβ and Gγ subunits that mediate the inhibition of synaptic transmission in mouse brain are identified.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference62 articles.

1. G protein βγ subunits: Central mediators of G protein-coupled receptor signaling

2. G-protein-coupled-receptor-mediated presynaptic inhibition in the cerebellum

3. Role of subunit diversity in signaling by heterotrimeric G proteins

4. Interaction between G-protein beta and gamma subunit types is selective.

5. Differential Ability to Form the G Protein βγ Complex among Members of the β and γ Subunit Families

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