Proteomic and Functional Genomic Landscape of Receptor Tyrosine Kinase and Ras to Extracellular Signal–Regulated Kinase Signaling-Reference-Cited by-同舟云学术

Proteomic and Functional Genomic Landscape of Receptor Tyrosine Kinase and Ras to Extracellular Signal–Regulated Kinase Signaling

Published:2011-10-25 Issue:196 Volume:4 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Friedman Adam A.¹²³,Tucker George⁴,Singh Rohit⁴,Yan Dong¹²,Vinayagam Arunachalam¹²,Hu Yanhui¹²,Binari Richard¹²,Hong Pengyu⁵,Sun Xiaoyun⁵,Porto Maura¹²,Pacifico Svetlana⁶,Murali Thilakam⁶,Finley Russell L.⁶,Asara John M.⁷⁸,Berger Bonnie⁴⁹,Perrimon Norbert¹²

Affiliation:

1. Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

2. Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.

3. Harvard–MIT Division of Health Sciences and Technology, Boston, MA 02115, USA.

4. Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

5. Department of Computer Science, Volen Center for Complex Systems, Brandeis University, Waltham, MA 02454, USA.

6. Center for Molecular Medicine and Genetics and Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201, USA.

7. Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.

8. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

9. Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Abstract

Interactome mapping and functional genomics in Drosophila reveal common and specific components of a mitogen-activated protein kinase pathway.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference61 articles.

1. K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer

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