Cbl Controls EGFR Fate by Regulating Early Endosome Fusion
Author:
Affiliation:
1. Department of Pharmacology, University of Iowa, Iowa City, IA 52242, USA.
2. Department of Pathology and the OSU Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Abstract
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference31 articles.
1. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
2. The Evolutionarily Conserved N-terminal Region of Cbl Is Sufficient to Enhance Down-regulation of the Epidermal Growth Factor Receptor
3. Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis
4. The Cbl RING finger C-terminal flank controls epidermal growth factor receptor fate downstream of receptor ubiquitination
5. Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
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