Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine-Reference-Cited by-同舟云学术

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Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine

Published:2021-08-24 Issue:697 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Döring Marius¹²^ORCID,De Azevedo Kevin¹^ORCID,Blanco-Rodriguez Guillermo¹,Nadalin Francesca¹^ORCID,Satoh Takeshi¹²^ORCID,Gentili Matteo¹^ORCID,Lahaye Xavier¹^ORCID,De Silva Nilushi S.¹,Conrad Cécile¹^ORCID,Jouve Mabel¹^ORCID,Centlivre Mireille²³^ORCID,Lévy Yves²³⁴^ORCID,Manel Nicolas¹²^ORCID

Affiliation:

1. Immunity and Cancer Department, Institut Curie, PSL Research University, INSERM U932, 75005 Paris, France.

2. Vaccine Research Institute (VRI), Créteil, Paris, France.

3. INSERM U955, Université Paris Est Créteil, Créteil, France.

4. AP-HP, Hôpital Henri-Mondor Albert-Chenevier, Service d’Immunologie Clinique et Maladies Infectieuses, Créteil, France.

Abstract

Infected and noninfected bystander dendritic cells have distinct roles in the response to the vaccine vector MVA.

Funder

European Molecular Biology Organization

Swedish International Development Corporation

ASCRS Research Foundation

Sidaction

Agence Nationale de la Recherche

European Commission

Deutsche Forschungsgemeinschaft

Labex VRI

LabEx DCBiol

Agence Nationale de Recherches sur le Sida et les Hepatites Virales

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference71 articles.

1. A. Volz G. Sutter in Advances in Virus Research (Elsevier 2017) vol. 97 pp. 187–243.

2. The Evolution of Poxvirus Vaccines

3. N. K. Routhu S. Gangadhara N. Cheedarla A. Shiferaw S. A. Rahman A. Sahoo P.-Y. Shi V. D. Menachery K. Floyd S. Fischinger C. Atyeo G. Alter M. S. Suthar R. R. Amara Modified vaccinia Ankara based SARS-CoV-2 vaccine expressing full-length spike induces strong neutralizing antibody response. bioRxiv 2020.06.27.175166 [ Preprint ]. 27 June 2020. https://doi.org/10.1101/2020.06.27.175166.

4. Intratumoral delivery of inactivated modified vaccinia virus Ankara (iMVA) induces systemic antitumor immunity via STING and Batf3-dependent dendritic cells

5. Organism-Level Analysis of Vaccination Reveals Networks of Protection across Tissues

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