Aberrant Ca 2+ signaling by IP 3 Rs in adipocytes links inflammation to metabolic dysregulation in obesity-Reference-Cited by-同舟云学术

Aberrant Ca 2+ signaling by IP 3 Rs in adipocytes links inflammation to metabolic dysregulation in obesity

Published:2021-12-14 Issue:713 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Guney Ekin¹^ORCID,Arruda Ana Paula¹^ORCID,Parlakgul Günes¹^ORCID,Cagampan Erika¹,Min Nina¹^ORCID,Lee Grace Yankun¹,Greene Lily¹^ORCID,Tsaousidou Eva¹,Inouye Karen¹^ORCID,Han Myoung Sook²^ORCID,Davis Roger J.²^ORCID,Hotamisligil Gökhan S.¹³^ORCID

Affiliation:

1. Sabri Ülker Center for Metabolic Research and Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

2. Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.

3. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Abstract

Inhibiting IP 3 Rs in adipocytes may prevent the development of obesity-induced metabolic complications.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference40 articles.

1. Inflammation, metaflammation and immunometabolic disorders

2. The many secret lives of adipocytes: implications for diabetes

3. Targeting adipose tissue in the treatment of obesity-associated diabetes