Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation-Reference-Cited by-同舟云学术

Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation

Published:2021-10-05 Issue:703 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

White Alex D.¹²^ORCID,Peña Karina A.¹^ORCID,Clark Lisa J.¹³^ORCID,Maria Christian Santa⁴^ORCID,Liu Shi⁵^ORCID,Jean-Alphonse Frédéric G.¹^ORCID,Lee Ji Young⁶^ORCID,Lei Saifei¹^ORCID,Cheng Zhiqiang⁴,Tu Chia-Ling⁴,Fang Fei¹^ORCID,Szeto Nicholas⁴,Gardella Thomas J.⁷,Xiao Kunhong¹^ORCID,Gellman Samuel H.⁵^ORCID,Bahar Ivet⁶^ORCID,Sutkeviciute Ieva¹^ORCID,Chang Wenhan⁴,Vilardaga Jean-Pierre¹^ORCID

Affiliation:

1. Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

2. Graduate Program in Molecular Pharmacology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

3. Graduate Program in Molecular Biology and Structural Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

4. Endocrine Research Unit, Department of Veterans Affairs Medical Center, and University of California, San Francisco, CA 94158, USA.

5. Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

6. Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.

7. Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Abstract

Physiological responses to parathyroid hormone depend on the subcellular location of receptor activity.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference67 articles.

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5. Sustained cyclic AMP production by parathyroid hormone receptor endocytosis

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