NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α-Reference-Cited by-同舟云学术

NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α

Published:2015-07-28 Issue:387 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Bao Chunyang¹,Li Yan¹²,Huan Lin¹,Zhang Yuannv¹,Zhao Fangyu¹,Wang Qifeng²,Liang Linhui²,Ding Jie²,Liu Li²,Chen Taoyang³,Li Jinjun¹,Yao Ming¹,Huang Shenglin²,He Xianghuo¹²

Affiliation:

1. State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200032, China.

2. Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.

3. Qidong Liver Cancer Institute, Qidong, Jiangsu 226200, China.

Abstract

Activation of NF-κB signaling in liver cancer cells suppresses a microRNA that usually limits NF-κB activity.

Funder

National 973 Key Basic Research Program

National Natural Science Foundation of China

Shanghai Municipal Health Bureau

Key Specialized Project for Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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