Antipsychotics Activate mTORC1-Dependent Translation to Enhance Neuronal Morphological Complexity-Reference-Cited by-同舟云学术

Antipsychotics Activate mTORC1-Dependent Translation to Enhance Neuronal Morphological Complexity

Published:2014-01-14 Issue:308 Volume:7 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Bowling Heather¹²,Zhang Guoan³,Bhattacharya Aditi⁴,Pérez-Cuesta Luis M.¹,Deinhardt Katrin¹,Hoeffer Charles A.²,Neubert Thomas A.³,Gan Wen-biao¹²,Klann Eric⁴,Chao Moses V.¹

Affiliation:

1. Departments of Cell Biology, Physiology and Neuroscience, and Psychiatry, Kimmel Center for Biology and Medicine at the Skirball Institute of Biomolecular Medicine, New York University Langone School of Medicine, New York, NY 10016, USA.

2. Department of Neuroscience and Physiology and Neuroscience, New York University Neuroscience Institute, New York University Langone Medical Center, New York, NY 10016, USA.

3. Department of Biochemistry and Molecular Pharmacology, Kimmel Center for Biology and Medicine at the Skirball Institute of Biomolecular Medicine, New York University Langone School of Medicine, New York, NY 10016, USA.

4. Center for Neural Science, New York University, New York, NY 10003, USA.

Abstract

By stimulating the synthesis of a distinct set of proteins, antipsychotics increase neuronal complexity.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference61 articles.

1. Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia

2. Evidence for Onset of Antipsychotic Effects Within the First 24 Hours of Treatment

3. Intramuscular Olanzapine and Intramuscular Haloperidol in Acute Schizophrenia: Antipsychotic Efficacy and Extrapyramidal Safety during the First 24 Hours of Treatment

4. Plasma Haloperidol Levels and Clinical Effects in Schizophrenia and Schizoaffective Disorder

5. Antipsychotic drug effects on the electrical activity of dopaminergic neurons

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