Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks-Reference-Cited by-同舟云学术

Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks

Published:2016-10-11 Issue:449 Volume:9 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Simmons Alan J.¹²,Scurrah Cherié R.¹²,McKinley Eliot T.¹³,Herring Charles A.¹⁴,Irish Jonathan M.⁵⁶,Washington M. Kay⁶,Coffey Robert J.¹²³⁷,Lau Ken S.¹²⁴

Affiliation:

1. Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

2. Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

3. Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

4. Chemical and Physical Biology Program, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

5. Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

6. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

7. Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN 37232, USA.

Abstract

A single-cell analytical approach in the clinic may lead to more effective treatment strategies for cancer patients.

Funder

American Association for Cancer Research–Landon Foundation

Crohn’s & Colitis Foundation of America Career Development Award

Vanderbilt Institute for Clinical and Translational Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference80 articles.

1. Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

2. Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

3. A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis

4. Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis

5. Single-cell dissection of transcriptional heterogeneity in human colon tumors

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