Hedgehog Signaling and the Gli Code in Stem Cells, Cancer, and MetastasesA Presentation from the 1st International HEALING Meeting: Hh-Gli Signaling in Development, Regeneration, and Disease, Kolymbari, Crete, 23 to 25 June 2011.-Reference-Cited by-同舟云学术

Hedgehog Signaling and the Gli Code in Stem Cells, Cancer, and MetastasesA Presentation from the 1st International HEALING Meeting: Hh-Gli Signaling in Development, Regeneration, and Disease, Kolymbari, Crete, 23 to 25 June 2011.

Published:2011-11-22 Issue:200 Volume:4 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Ruiz i Altaba Ariel¹

Affiliation:

1. University of Geneva Medical School, 8242 Centre Médicale Universitaire, 1 rue Michel Servet, CH-1211 Geneva 4, Switzerland.

Abstract

Hedgehog signaling and the oncogenic load promote stem cell–like behavior and metastasis by influencing the balance between activator and repressor functions of Gli transcription factors.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference55 articles.

1. Sonic hedgehog regulates the growth and patterning of the cerebellum

2. Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

3. Control of Neuronal Precursor Proliferation in the Cerebellum by Sonic Hedgehog

4. The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis

5. HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity

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