Integrating network reconstruction with mechanistic modeling to predict cancer therapies-Reference-Cited by-同舟云学术

Integrating network reconstruction with mechanistic modeling to predict cancer therapies

Author:

Halasz Melinda¹²,Kholodenko Boris N.¹²³,Kolch Walter¹²³,Santra Tapesh¹

Affiliation:

1. Systems Biology Ireland, University College Dublin, Belfield, Dublin 4, Ireland.

2. School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.

3. Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.

Abstract

Unexpected drug combinations for cancer treatment emerge from modeling signaling pathways affected by genomic mutations.

Funder

Science Foundation Ireland

European Union FP7

Irish Cancer Society Collaborative Cancer Research Centre BREAST-PREDICT

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference81 articles.

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