Evolution of human, chicken, alligator, frog, and zebrafish mineralocorticoid receptors: Allosteric influence on steroid specificity-Reference-Cited by-同舟云学术

Evolution of human, chicken, alligator, frog, and zebrafish mineralocorticoid receptors: Allosteric influence on steroid specificity

Published:2018-07-03 Issue:537 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Katsu Yoshinao¹²^ORCID,Oka Kaori¹,Baker Michael E.³^ORCID

Affiliation:

1. Graduate School of Life Science, Hokkaido University, Sapporo, Japan.

2. Department of Biological Sciences, Hokkaido University, Sapporo, Japan.

3. Division of Nephrology-Hypertension, Department of Medicine, University of California, San Diego, La Jolla, CA 92093–0693, USA.

Abstract

Analysis of the interactions of multiple steroid ligands with the mineralocorticoid receptor identifies domains involved in activation and inhibition.

Funder

Ministry of Education, Culture, Sports, Science and Technology of Japan

Research fund #3096

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference72 articles.

1. Independent elaboration of steroid hormone signaling pathways in metazoans

2. Protein Evolution by Molecular Tinkering: Diversification of the Nuclear Receptor Superfamily from a Ligand-Dependent Ancestor

3. Nuclear hormone receptors in chordates

4. Origin of the response to adrenal and sex steroids: Roles of promiscuity and co-evolution of enzymes and steroid receptors

5. Aldosterone and mineralocorticoid receptors: A personal reflection

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