The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK-Reference-Cited by-同舟云学术

The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK

Published:2017-09-19 Issue:497 Volume:10 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Amin Elianna M.¹^ORCID,Liu Yuan¹,Deng Su¹,Tan Kay See²^ORCID,Chudgar Neel¹^ORCID,Mayo Marty W.³^ORCID,Sanchez-Vega Francisco²,Adusumilli Prasad S.¹^ORCID,Schultz Nikolaus²,Jones David R.¹^ORCID

Affiliation:

1. Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

2. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

3. Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA.

Abstract

Editing of FAK mRNA by the enzyme ADAR in lung adenocarcinoma cells promotes migration and invasion.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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5. The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

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