Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome-Reference-Cited by-同舟云学术

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

Author:

Pyronneau Alexander¹^ORCID,He Qionger²,Hwang Jee-Yeon¹^ORCID,Porch Morgan¹^ORCID,Contractor Anis²³^ORCID,Zukin R. Suzanne¹^ORCID

Affiliation:

1. Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.

2. Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

3. Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, Evanston, IL 60208, USA.

Abstract

Inhibiting Rac1-PAK-LIMK signaling may restore synaptic function and sensory processing in patients with fragile X syndrome.

Funder

National Institutes of Health

National Institute of Mental Health

Brain and Behavior Research Foundation

McKnight Foundation

National Institute of General Medical Sciences

American Heart Association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference77 articles.

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