Signaling by the inhibitory receptor CD200R is rewired by type I interferon-Reference-Cited by-同舟云学术

Signaling by the inhibitory receptor CD200R is rewired by type I interferon

Published:2021-10-12 Issue:704 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

van der Vlist Michiel¹²^ORCID,Ramos M. Inês Pascoal¹²^ORCID,van den Hoogen Lucas L.³,Hiddingh Sanne¹^ORCID,Timmerman Laura M.¹²^ORCID,de Hond Titus A. P.¹²,Kaan Ellen D.¹²^ORCID,van der Kroef Maarten³,Lebbink Robert Jan⁴^ORCID,Peters Florence M. A.¹^ORCID,Khoury-Hanold William⁵^ORCID,Fritsch-Stork Ruth³,Radstake Timothy R. D. J.³^ORCID,Meyaard Linde¹²^ORCID

Affiliation:

1. Center for Translational Immunology, Department of Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

2. Oncode Institute, Utrecht, Netherlands.

3. Center for Translational Immunology, Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

4. Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

5. Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

Abstract

Type I interferon switches the receptor CD200R from inhibiting to potentiating inflammatory responses in immune cells.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference68 articles.

1. Immune Inhibitory Receptors

2. Lymphoid/Neuronal Cell Surface OX2 Glycoprotein Recognizes a Novel Receptor on Macrophages Implicated in the Control of Their Function

3. Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice