Protein Tyrosine Phosphatase 1B Is a Regulator of the Interleukin-10–Induced Transcriptional Program in Macrophages-Reference-Cited by-同舟云学术

Protein Tyrosine Phosphatase 1B Is a Regulator of the Interleukin-10–Induced Transcriptional Program in Macrophages

Published:2014-05-06 Issue:324 Volume:7 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Pike Kelly A.¹,Hutchins Andrew P.²³,Vinette Valerie¹⁴,Théberge Jean-François¹,Sabbagh Laurent⁵,Tremblay Michel L.¹⁴,Miranda-Saavedra Diego²⁶

Affiliation:

1. Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue, Montreal, Quebec H3A 1A3, Canada.

2. World Premier International (WPI) Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, 565-0871 Osaka, Japan.

3. South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kaiyuan Avenue, Guangzhou 510663, China.

4. Department of Biochemistry, McGill University, 3655 Promenade Sir William Osler, Montreal, Quebec H3G 1Y6, Canada.

5. Department of Microbiology, Infectiology and Immunology, University of Montreal, CP 6128 Succursale Centre-Ville, Montreal, Quebec H3C 3J7, Canada.

6. Fibrosis Laboratories, Institute of Cellular Medicine, Newcastle University Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

Abstract

The specificity of cytokine target genes may be fine-tuned by protein tyrosine phosphatases.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference56 articles.

1. Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

2. STATs: transcriptional control and biological impact

3. Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways

4. SOCS3 negatively regulates IL-6 signaling in vivo

5. SOCS3 regulates the plasticity of gp130 signaling

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