β-Arrestin–dependent ERK signaling reduces anxiety-like and conditioned fear–related behaviors in mice-Reference-Cited by-同舟云学术

β-Arrestin–dependent ERK signaling reduces anxiety-like and conditioned fear–related behaviors in mice

Published:2021-08-03 Issue:694 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Ko Mee Jung¹²³^ORCID,Chiang Terrance¹,Mukadam Arbaaz A.¹⁴,Mulia Grace E.¹³^ORCID,Gutridge Anna M.¹²^ORCID,Lin Angel¹,Chester Julia A.²³⁴^ORCID,van Rijn Richard M.¹²³⁵^ORCID

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.

2. Purdue Institute for Integrative Neuroscience, West Lafayette, IN 47907, USA.

3. Purdue Interdisciplinary Life Sciences Graduate Program, West Lafayette, IN 47907, USA.

4. Department of Psychological Sciences, College of Health and Human Sciences, Purdue University, West Lafayette, IN 47907, USA.

5. Purdue Institute for Drug Discovery, West Lafayette, IN 47907, USA.

Abstract

β-Arrestin signaling may mediate the fear- and anxiety-relieving effects as well as adverse events of opioids.

Funder

National Institute on Drug Abuse

National Institute on Alcohol Abuse and Alcoholism

ASCRS Research Foundation

Drug Abuse

Brain and Behavior Research Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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