Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation-Reference-Cited by-同舟云学术

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

Published:2018-07-24 Issue:540 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Bagnall James¹^ORCID,Boddington Christopher¹,England Hazel¹^ORCID,Brignall Ruth¹,Downton Polly¹^ORCID,Alsoufi Zainab²^ORCID,Boyd James¹³^ORCID,Rowe William¹⁴,Bennett Alexander¹,Walker Catherine¹^ORCID,Adamson Antony¹^ORCID,Patel Nisha M. X.¹^ORCID,O’Cualain Ronan¹,Schmidt Lorraine¹,Spiller David G.¹,Jackson Dean A.¹^ORCID,Müller Werner¹^ORCID,Muldoon Mark²^ORCID,White Michael R. H.¹^ORCID,Paszek Pawel¹^ORCID

Affiliation:

1. Faculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

2. School of Mathematics, University of Manchester, Manchester M13 9PL, UK.

3. Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3BX, UK.

4. Department of Chemistry, Centre for Analytical Science, Loughborough University, Loughborough LE11 3TU, UK.

Abstract

Competitive TNF-α uptake regulates the propagation of heterogeneous responses of macrophages in tissues.

Funder

Wellcome Trust

Medical Research Council

Biotechnology and Biological Sciences Research Council

Seventh Framework Programme