1. Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec H3G 1Y6, Canada.
2. Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
3. Department of Medicine, McGill University Health Center, McGill University, Montréal, Québec H4A 3J1, Canada.
4. Department of Pharmacology-Physiology, Université de Sherbrooke, Sherbrooke, Québec J1H 5N4, Canada.