Leukotriene B 4 –mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes-Reference-Cited by-同舟云学术

Leukotriene B 4 –mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes

Published:2015-01-27 Issue:361 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Filgueiras Luciano Ribeiro¹²,Brandt Stephanie L.¹,Wang Soujuan¹,Wang Zhuo¹,Morris David L.³,Evans-Molina Carmella³,Mirmira Raghavendra G.³,Jancar Sonia²,Serezani C. Henrique¹

Affiliation:

1. Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

2. Immunology Department, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508, Brazil.

3. Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Abstract

Inhibiting the production of a leukotriene may help type 1 diabetic patients from succumbing to sepsis.

Funder

NIH

Ralph W. and Grace M. Showalter Research Trust Fund

Veteran';s Affairs (VA) Merit Award

Sigma Beta Sorority

Ball Brothers Foundation

George and Frances Ball Foundation

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference83 articles.

1. Mechanisms of joint damage in gout: evidence from cellular and imaging studies

2. β-Cell Mass and Type 1 Diabetes

3. Anti-Inflammatory Therapy in Type 1 Diabetes

4. Molecular determinants of sterile inflammation

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