Abl Family Kinases Modulate T Cell–Mediated Inflammation and Chemokine-Induced Migration Through the Adaptor HEF1 and the GTPase Rap1-Reference-Cited by-同舟云学术

Abl Family Kinases Modulate T Cell–Mediated Inflammation and Chemokine-Induced Migration Through the Adaptor HEF1 and the GTPase Rap1

Author:

Gu Jing Jin¹,Lavau Catherine P.²,Pugacheva Elena³,Soderblom Erik J.⁴,Moseley M. Arthur⁴,Pendergast Ann Marie¹

Affiliation:

1. Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA.

2. Pediatric Hematology-Oncology, Duke University School of Medicine, Durham, NC 27710, USA.

3. Department of Biochemistry, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.

4. Proteomics Core Facility, Institute for Genome Sciences & Policy, Duke University, Durham, NC 27710, USA.

Abstract

Inhibitors of Abl family kinases block T cell migration and could be used to treat inflammatory diseases.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference39 articles.

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