Emerging concepts in pseudoenzyme classification, evolution, and signaling

Author:

Ribeiro António J. M.1ORCID,Das Sayoni2ORCID,Dawson Natalie2,Zaru Rossana1ORCID,Orchard Sandra1ORCID,Thornton Janet M.1ORCID,Orengo Christine2,Zeqiraj Elton3,Murphy James M.45ORCID,Eyers Patrick A.6ORCID

Affiliation:

1. European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

2. Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK.

3. Astbury Centre for Structural Molecular Biology, Molecular and Cellular Biology, Faculty of Biological Sciences, Astbury Building, Room 8.109, University of Leeds, Leeds LS2 9JT, UK.

4. Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia.

5. Department of Medical Biology, University of Melbourne, Parkville, Victoria 3052, Australia.

6. Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.

Abstract

A roadmap for identifying and analyzing pseudoenzymes is proposed for this rapidly expanding field.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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