Two Receptors, Two Kinases, and T Cell Lineage Determination-Reference-Cited by-同舟云学术

Two Receptors, Two Kinases, and T Cell Lineage Determination

Published:2010-03-23 Issue:114 Volume:3 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Alarcón Balbino¹,van Santen Hisse M.¹

Affiliation:

1. Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Cantoblanco, Madrid 28049, Spain.

Abstract

Specification of T cell lineage in the thymus is controlled by the timing and strength of signaling of the tyrosine kinase Zap70.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference25 articles.

1. Development of the CD4 and CD8 lineage of T cells: instruction versus selection.

2. Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage

3. Development of all CD4 T lineages requires nuclear factor TOX

4. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment

5. GATA-3 Expression Is Controlled by TCR Signals and Regulates CD4/CD8 Differentiation

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