Charting the Landscape of Tandem BRCT Domain–Mediated Protein Interactions-Reference-Cited by-同舟云学术

Charting the Landscape of Tandem BRCT Domain–Mediated Protein Interactions

Published:2012-09-18 Issue:242 Volume:5 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Woods Nicholas T.¹,Mesquita Rafael D.²,Sweet Michael¹³,Carvalho Marcelo A.²⁴,Li Xueli¹,Liu Yun⁵,Nguyen Huey¹,Thomas C. Eric⁶,Iversen Edwin S.⁷,Marsillac Sylvia¹,Karchin Rachel⁵,Koomen John⁶,Monteiro Alvaro N. A.¹

Affiliation:

1. Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

2. Instituto Federal de Educação, Ciência e Tecnologia, Rio de Janeiro, RJ 20270, Brazil.

3. Graduate Program in Biomedical Sciences, College of Medicine, University of South Florida, Tampa, FL 33612, USA.

4. Instituto Nacional do Câncer, Rio de Janeiro, RJ 20231, Brazil.

5. Institute for Computational Medicine, Department of Biochemical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

6. Molecular Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

7. Department of Statistical Science, Duke University, Durham, NC 27708, USA.

Abstract

Building a protein-protein interaction network mediated by the BRCT domain reveals players in the DNA damage response.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference93 articles.

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2. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

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4. Inhibition of Poly(ADP-Ribose) Polymerase in Tumors fromBRCAMutation Carriers

5. DNA repair pathways as targets for cancer therapy

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