Inhibition of somatosensory mechanotransduction by annexin A6-Reference-Cited by-同舟云学术

Inhibition of somatosensory mechanotransduction by annexin A6

Published:2018-06-19 Issue:535 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Raouf Ramin¹^ORCID,Lolignier Stéphane¹^ORCID,Sexton Jane E.¹^ORCID,Millet Queensta¹,Santana-Varela Sonia¹,Biller Anna¹^ORCID,Fuller Alice M.¹^ORCID,Pereira Vanessa¹^ORCID,Choudhary Jyoti S.²,Collins Mark O.³^ORCID,Moss Stephen E.⁴^ORCID,Lewis Richard⁵^ORCID,Tordo Julie⁶,Henckaerts Els⁶^ORCID,Linden Michael⁶^ORCID,Wood John N.¹^ORCID

Affiliation:

1. Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London (UCL), Gower Street, London WC1E 6BT, UK.

2. Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

3. Department of Biomedical Science, The University of Sheffield, Western Bank, Sheffield S10 2TN, UK.

4. Institute of Ophthalmology, UCL, 11-43 Bath Street, London EC1V 9EL, UK.

5. Institute for Molecular Bioscience, University of Queensland, Brisbane, St. Lucia, Queensland 4072, Australia.

6. Department of Infectious Diseases, King’s College London School of Medicine, London SE1 9RT, UK.

Abstract

The membrane-binding protein annexin A6 suppresses mechanically induced pain in a mouse model of osteoarthritis.

Funder

Wellcome Trust

Arthritis Research UK

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference46 articles.

1. Estimates of Pain Prevalence and Severity in Adults: United States, 2012

2. Mechanical transduction by rat dorsal root ganglion neurons in vitro

3. Modulation of sensory neuron mechanotransduction by PKC- and nerve growth factor-dependent pathways

4. Distinct Mechanosensitive Properties of Capsaicin-Sensitive and -Insensitive Sensory Neurons

5. Piezo2 is the major transducer of mechanical forces for touch sensation in mice

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