Itk Controls the Spatiotemporal Organization of T Cell Activation-Reference-Cited by-同舟云学术

Itk Controls the Spatiotemporal Organization of T Cell Activation

Published:2011-10-04 Issue:193 Volume:4 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Singleton Kentner L.¹,Gosh Monica¹,Dandekar Radhika D.¹,Au-Yeung Byron B.²,Ksionda Olga³,Tybulewicz Victor L. J.³,Altman Amnon⁴,Fowell Deborah J.²,Wülfing Christoph¹⁵

Affiliation:

1. Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

2. David H. Smith Center for Vaccine Biology and Immunology, Aab Institute of Biomedical Sciences, Department of Microbiology and Immunology, University of Rochester, Rochester, NY 14642, USA.

3. Division of Immune Cell Biology, Medical Research Council, National Institute for Medical Research, London NW7 1AA, UK.

4. Division of Cell Biology, La Jolla Institute for Allergy and Immunology, San Diego, CA 92121, USA.

5. Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Abstract

Loss of the kinase Itk in activated T cells disrupts actin accumulation at the immunological synapse, compromising T cell activation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference45 articles.

1. The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

2. Selective modulation of protein kinase C-Θ during T-cell activation

3. Spatiotemporal Patterning During T Cell Activation Is Highly Diverse

4. T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells

5. Protein Kinase C-θ Mediates Negative Feedback on Regulatory T Cell Function

Cited by 48 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. TIM3 is a context-dependent co-regulator of cytotoxic T cell function;2023-08-05

2. DEF6(differentially exprehomolog) exacerbates pathological cardiac hypertrophy via RAC1;Cell Death & Disease;2023-07-31

3. Regulation of Cx43 Gap Junction Intercellular Communication by Bruton’s Tyrosine Kinase and Interleukin-2-Inducible T-Cell Kinase;Biomolecules;2023-04-08

4. Cellular Structures Controlling T Cell Signaling in Time and Space;Encyclopedia of Cell Biology;2023

5. Molecular mechanisms controlling age‐associated B cells in autoimmunity*;Immunological Reviews;2022-01-31