Dissecting the biology of mTORC1 beyond rapamycin-Reference-Cited by-同舟云学术

Dissecting the biology of mTORC1 beyond rapamycin

Published:2021-09-21 Issue:701 Volume:14 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Yang Guang¹^ORCID,Francis Deanne¹^ORCID,Krycer James R.¹^ORCID,Larance Mark¹,Zhang Ziyang²^ORCID,Novotny Chris J.²^ORCID,Diaz-Vegas Alexis¹^ORCID,Shokat Kevan M.²^ORCID,James David E.¹³^ORCID

Affiliation:

1. University of Sydney, School of life and Environmental Sciences, Charles Perkins Centre, Sydney, New South Wales 2006, Australia.

2. Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, University of California, San Francisco, 600 16th Street, San Francisco, CA 94143, USA.

3. University of Sydney, Sydney Medical School, Sydney, New South Wales 2006, Australia.

Abstract

RapaLink1 enables differentiation between functions mediated by the closely related mTORC1 and mTORC2.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference61 articles.

1. mTOR Signaling in Growth, Metabolism, and Disease

2. mTORC1 signaling and the metabolic control of cell growth

3. Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s Disease

4. SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity

5. Fat Cell–Specific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism

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