Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway-Reference-Cited by-同舟云学术

Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway

Published:2020-05-05 Issue:630 Volume:13 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Duron David I.¹^ORCID,Lei Wei¹^ORCID,Barker Natalie K.²^ORCID,Stine Carrie¹^ORCID,Mishra Sanket³,Blagg Brian S. J.³,Langlais Paul R.²^ORCID,Streicher John M.¹^ORCID

Affiliation:

1. Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.

2. Division of Endocrinology, Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.

3. Department of Chemistry and Biochemistry, College of Science, University of Notre Dame, Notre Dame, IN 46556, USA.

Abstract

Spinal delivery of Hsp90 inhibitors may make opioids safer and more effective.

Funder

University of Arizona

Arizona Biomedical Research Commission

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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