A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells-Reference-Cited by-同舟云学术

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

Published:2018-06-12 Issue:534 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Tsutsui Kenta¹^ORCID,Monfredi Oliver J.¹²³^ORCID,Sirenko-Tagirova Syevda G.¹,Maltseva Larissa A.¹,Bychkov Rostislav¹,Kim Mary S.¹,Ziman Bruce D.¹,Tarasov Kirill V.¹,Tarasova Yelena S.¹,Zhang Jing¹,Wang Mingyi¹,Maltsev Alexander V.¹,Brennan Jaclyn A.⁴^ORCID,Efimov Igor R.⁴,Stern Michael D.¹^ORCID,Maltsev Victor A.¹^ORCID,Lakatta Edward G.¹

Affiliation:

1. Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, MD 21224, USA.

2. Institute of Cardiovascular Sciences, University of Manchester, Manchester M13 9NT, UK.

3. Department of Cardiovascular Electrophysiology, Johns Hopkins Hospital, 1800 Orleans Street, Baltimore, MD 21287, USA.

4. Department of Biomedical Engineering, George Washington University, Washington, DC 20052, USA.

Abstract

The mechanisms that generate pacemaking activity in human sinoatrial nodal cells are revealed.

Funder

National Institutes of Health

National Institute on Aging

National Institute for Health Research

Fondation Leducq

Japan Society for the Promotion of Science

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference29 articles.

1. Intracellular Ca 2+ release contributes to automaticity in cat atrial pacemaker cells

2. Sinoatrial Nodal Cell Ryanodine Receptor and Na + -Ca 2+ Exchanger

3. A Coupled SYSTEM of Intracellular Ca 2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heart’s Pacemaker

4. Rhythmic Ryanodine Receptor Ca 2+ Releases During Diastolic Depolarization of Sinoatrial Pacemaker Cells Do Not Require Membrane Depolarization

5. High Basal Protein Kinase A–Dependent Phosphorylation Drives Rhythmic Internal Ca 2+ Store Oscillations and Spontaneous Beating of Cardiac Pacemaker Cells

Cited by 83 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Modeling the atrioventricular conduction axis using human pluripotent stem cell-derived cardiac assembloids;Cell Stem Cell;2024-09

2. A modified method for isolating sinoatrial node myocytes from adult mice;In Vitro Cellular & Developmental Biology - Animal;2024-06-19

3. Pacemaker Channels and the Chronotropic Response in Health and Disease;Circulation Research;2024-05-10

4. From Psychostasis to the Discovery of Cardiac Nerves: The Origins of the Modern Cardiac Neuromodulation Concept;Biology;2024-04-16

5. Activation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP;2024-03-30