TRAF6 Stimulates the Tumor-Promoting Effects of TGFβ Type I Receptor Through Polyubiquitination and Activation of Presenilin 1
Author:
Affiliation:
1. Department of Medical Biosciences, Pathology, Umeå University, SE-901 85 Umeå, Sweden.
2. Ludwig Institute for Cancer Research, Science for Life Laboratory, Uppsala University, SE-751 85 Uppsala, Sweden.
Abstract
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference48 articles.
1. TGFβ in Cancer
2. Mechanism of TGF-β signaling to growth arrest, apoptosis, and epithelial–mesenchymal transition
3. Mechanism of activation of the TGF-β receptor
4. MADR2 Is a Substrate of the TGFβ Receptor and Its Phosphorylation Is Required for Nuclear Accumulation and Signaling
5. Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling
Cited by 63 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. TRAF6 enhances PD-L1 expression through YAP1-TFCP2 signaling in melanoma;Cancer Letters;2024-05
2. Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor;European Journal of Medicinal Chemistry;2024-05
3. Targeting SMAD-Dependent Signaling: Considerations in Epithelial and Mesenchymal Solid Tumors;Pharmaceuticals;2024-03-01
4. Tumor Necrosis Factor Receptor-Associated Factor 6 and Human Cancer: A Systematic Review of Mechanistic Insights, Functional Roles, and Therapeutic Potential;Journal of Cancer;2024
5. Ubiquitin Engineering for Interrogating the Ubiquitin–Proteasome System and Novel Therapeutic Strategies;Cells;2023-08-21
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3