Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH-Reference-Cited by-同舟云学术

Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH

Published:2018-11-06 Issue:555 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Zhou Dalee¹^ORCID,Ota Koji¹,Nardin Charlee¹²,Feldman Michelle¹^ORCID,Widman Adam¹^ORCID,Wind Olivia¹^ORCID,Simon Amanda¹^ORCID,Reilly Michael¹^ORCID,Levin Lonny R.³^ORCID,Buck Jochen³^ORCID,Wakamatsu Kazumasa⁴^ORCID,Ito Shosuke⁴,Zippin Jonathan H.¹^ORCID

Affiliation:

1. Department of Dermatology, Weill Cornell Medical College, New York, NY 10021, USA.

2. Service de Dermatologie, Centre Hospitalier Universitaire, Besançon 25030, France.

3. Department of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.

4. Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake 470-1192, Japan.

Abstract

Inhibitors of soluble adenylyl cyclase increase pigmentation and may reduce the risk of skin cancer.

Funder

National Cancer Institute

National Institute of General Medical Sciences

National Institute of Child Health and Human Development

American Skin Association

Melanoma Research Alliance

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference91 articles.

1. Regulation of melanogenesis - controversies and new concepts

2. Advances in Melanocyte Basic Science Research

3. Genome-Wide Association Shows that Pigmentation Genes Play a Role in Skin Aging

4. Genetics of pigmentation in skin cancer — A review

5. Chapter 4 The Melanocortin‐1 Receptor Gene Polymorphism and Association with Human Skin Cancer

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