Endothelium-targeted deletion of the miR-15a/16-1 cluster ameliorates blood-brain barrier dysfunction in ischemic stroke-Reference-Cited by-同舟云学术

Endothelium-targeted deletion of the miR-15a/16-1 cluster ameliorates blood-brain barrier dysfunction in ischemic stroke

Published:2020-04-07 Issue:626 Volume:13 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Ma Feifei¹^ORCID,Sun Ping¹^ORCID,Zhang Xuejing¹^ORCID,Hamblin Milton H.²,Yin Ke-Jie¹³^ORCID

Affiliation:

1. Pittsburgh Institute of Brain Disorders and Recovery, Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

2. Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

3. Geriatric Research, Education and Clinical Center, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15261, USA.

Abstract

Targeting of Claudin-5 by a microRNA cluster may contribute to blood-brain barrier leakage after stroke.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference52 articles.

1. Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

2. Astrocyte–endothelial interactions at the blood–brain barrier

3. Establishment and Dysfunction of the Blood-Brain Barrier

4. Stroke research at a crossroad: asking the brain for directions

5. Structural and functional aspects of the blood-brain barrier;Begley D. J.;Prog. Drug Res.,2003

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