Lipocalin 2 from macrophages stimulated by tumor cell–derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis-Reference-Cited by-同舟云学术

Lipocalin 2 from macrophages stimulated by tumor cell–derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis

Published:2016-06-28 Issue:434 Volume:9 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Jung Michaela¹,Ören Bilge¹,Mora Javier¹²,Mertens Christina¹,Dziumbla Sarah³,Popp Rüdiger³,Weigert Andreas¹,Grossmann Nina¹,Fleming Ingrid³,Brüne Bernhard¹

Affiliation:

1. Institute of Biochemistry I, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

2. Faculty of Microbiology, University of Costa Rica, 2060 San José, Costa Rica.

3. Institute for Vascular Signalling, Goethe-University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

Abstract

Dying tumor cells trigger a macrophage response that stimulates lymphangiogenesis.

Funder

Fritz Thyssen Stiftung

Goethe-University Frankfurt

Doktor Robert Pfleger-Stiftung

Monika Kutzner Stiftung

SFB 1039

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference57 articles.

1. Tumor-associated macrophages: functional diversity, clinical significance, and open questions

2. Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment

3. Microenvironmental regulation of tumor progression and metastasis

4. The Many Alternative Faces of Macrophage Activation

5. The liaison between apoptotic cells and macrophages – the end programs the beginning

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