Attenuation of Rabies Virulence: Takeover by the Cytoplasmic Domain of Its Envelope Protein-Reference-Cited by-同舟云学术

Attenuation of Rabies Virulence: Takeover by the Cytoplasmic Domain of Its Envelope Protein

Published:2010-01-19 Issue:105 Volume:3 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Préhaud Christophe¹²³,Wolff Nicolas¹⁴⁵,Terrien Elouan¹⁴⁵,Lafage Mireille¹²³,Mégret Françoise¹²³,Babault Nicolas¹⁴⁵,Cordier Florence¹⁴⁵,Tan Gene S.⁶,Maitrepierre Elodie¹⁴⁵,Ménager Pauline¹²³,Chopy Damien¹²³,Hoos Sylviane¹⁵⁷,England Patrick¹⁵⁷,Delepierre Muriel¹⁴⁵,Schnell Matthias J.⁶,Buc Henri¹,Lafon Monique¹²³

Affiliation:

1. Institut Pasteur, 75724 Paris, France.

2. Unité de Neuroimmunologie Virale, Département de Virologie, Institut Pasteur, 75724 Paris, France.

3. CNRS URA 3015, Institut Pasteur, 75724 Paris, France.

4. Unité de Résonance Magnétique Nucléaire des Biomolécules, Département de Biologie Structurale et Chimie, Institut Pasteur, 75724 Paris, France.

5. CNRS URA 2185, Institut Pasteur, 75724 Paris, France.

6. Department of Microbiology and Immunology, and Jefferson Vaccine Centre, Thomas Jefferson University, Philadelphia, PA 19107–5541, USA.

7. Plateforme de Biophysique des Macromolécules et de leurs Interactions, Institut Pasteur, 75724 Paris, France.

Abstract

Survival of rabies virus–infected neurons depends on a single amino acid in the PDZ-binding site of a viral protein.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference36 articles.

1. Glycoprotein of Nonpathogenic Rabies Viruses Is a Key Determinant of Human Cell Apoptosis

2. Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein

3. Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells

4. Vinculin Controls PTEN Protein Level by Maintaining the Interaction of the Adherens Junction Protein β-Catenin with the Scaffolding Protein MAGI-2

5. Binding of PTEN to Specific PDZ Domains Contributes to PTEN Protein Stability and Phosphorylation by Microtubule-associated Serine/Threonine Kinases

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