BSTA Promotes mTORC2-Mediated Phosphorylation of Akt1 to Suppress Expression of FoxC2 and Stimulate Adipocyte Differentiation-Reference-Cited by-同舟云学术

BSTA Promotes mTORC2-Mediated Phosphorylation of Akt1 to Suppress Expression of FoxC2 and Stimulate Adipocyte Differentiation

Published:2013-01-08 Issue:257 Volume:6 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Yao Yixin¹,Suraokar Milind²,Darnay Bryant G.³,Hollier Brett G.⁴,Shaiken Tattym E.⁵,Asano Takayuki¹,Chen Chien-Hung⁵,Chang Benny H.-J.⁶,Lu Yiling⁷,Mills Gordon B.⁷,Sarbassov Dos⁵,Mani Sendurai A.⁴,Abbruzzese James L.¹,Reddy Shrikanth A. G.¹

Affiliation:

1. Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

2. Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

3. Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

4. Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

5. Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

6. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

7. Department of Systems Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

Abstract

Activation of Akt1 during adipocyte differentiation requires a binding partner called BSTA.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference60 articles.

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2. PI3K/Akt: getting it right matters

3. Advances in protein kinase B signalling: AKTion on multiple fronts☆

4. Protein kinases, from B to C

5. New Insights into mTOR Signaling: mTORC2 and Beyond

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