Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs-Reference-Cited by-同舟云学术

Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs

Published:2010-02-16 Issue:109 Volume:3 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Mok Janine¹,Kim Philip M.²,Lam Hugo Y. K.³,Piccirillo Stacy¹,Zhou Xiuqiong¹,Jeschke Grace R.⁴,Sheridan Douglas L.⁴,Parker Sirlester A.⁴,Desai Ved⁴,Jwa Miri⁵,Cameroni Elisabetta⁶,Niu Hengyao⁷,Good Matthew⁸,Remenyi Attila⁸,Ma Jia-Lin Nianhan⁹,Sheu Yi-Jun¹⁰,Sassi Holly E.¹¹,Sopko Richelle¹¹,Chan Clarence S. M.⁵,De Virgilio Claudio⁶,Hollingsworth Nancy M.⁷,Lim Wendell A.¹²,Stern David F.⁹,Stillman Bruce¹⁰,Andrews Brenda J.¹¹,Gerstein Mark B.²³,Snyder Michael¹²,Turk Benjamin E.⁴

Affiliation:

1. Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA.

2. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.

3. Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.

4. Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.

5. Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA.

6. Department of Medicine, Division of Biochemistry, University of Fribourg, CH-1700 Fribourg, Switzerland.

7. Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY 11794, USA.

8. Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA.

9. Department of Pathology, School of Medicine, Yale University, New Haven, CT 06520, USA.

10. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

11. Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada M5S 3E1.

12. Eötvös Loránd University, Department of Biochemistry and Howard Hughes Medical Institute, Pázmány Péter sétány 1/C, H-1117 Budapest, Hungary.

Abstract

A high-throughput peptide array approach reveals insight into kinase substrates and specificity.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference74 articles.

1. Evolution of protein kinase signaling from yeast to man

2. Building mammalian signalling pathways with RNAi screens

3. Phosphoproteomic approaches to elucidate cellular signaling networks

4. Global analysis of protein phosphorylation in yeast

5. Using Chemical Genetics and ATP Analogues To Dissect Protein Kinase Function

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